RAF Typhoon FGR4s have operated alongside France's air force in a joint strike targeting an underground arms cache in Syria used by the Islamic State group (IS), per a report from the British defence ministry.
The location, pinpointed through intelligence, was believed to be housing weapons and explosive materials, the announcement noted, and was situated in hills just above the ancient city of Palmyra in the heart of Syria.
"The RAF jets employed laser-guided Paveway IV weapons to strike a number of access tunnels down to the site... initial indications are that the target was engaged successfully," the ministry announced.
There was no sign of any harm to civilians in the attack late on Saturday and each participating jet returned safely, the defence officials confirmed.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
Daesh - referred to as the so-called Islamic State - established extremist governance over large swathes of Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and determination to work closely with our allies, to eradicate any revival of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary the Defence Secretary remarked.
UK warplanes have conducted overwatch operations over Syrian airspace to "prevent any attempted comeback" of Islamic State subsequent to its military defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I extend gratitude to all the members of British forces who took part in this mission for their professionalism and their valour," Healey said. "They were part of a great many British personnel stationed over the festive period. This mission, to remove terrorist threats who endanger our safety, demonstrates how our armed forces are prepared to act, throughout the year, keeping Britain secure within its borders and strong abroad."
Last December, the United States armed forces conducted what it described as a "large-scale strike" on Daesh sites in Syria, subsequent to an assault claimed the lives of two US troops and a civilian interpreter in Palmyra.
The UN says IS still has an estimated 5,000 to 7,000 fighters in both countries.